Pitfalls in measuring the endocannabinoid 2-arachidonoyl glycerol in biological samples
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منابع مشابه
Pitfalls in measuring the endocannabinoid 2-arachidonoyl glycerol in biological samples.
BACKGROUND The endocannabinoid 2-arachidonoyl glycerol (2-AG) undergoes spontaneous isomerization to biologically inactive 1-AG. This effect has not been adequately addressed in previous studies that reported 2-AG concentrations in biological samples. METHODS Liquid chromatography tandem-mass spectrometry (LC-MS/MS) was used for 1-AG and 2-AG analyses. RESULTS Identical collision-induced di...
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Although endocannabinoids are important players in nociception and obesity, their roles as immunomodulators remain elusive. The main endocannabinoids described to date, namely 2-arachidonoyl-glycerol (2-AG) and arachidonyl-ethanolamide (AEA), induce an intriguing profile of pro- and anti-inflammatory effects. This could relate to cell-specific cannabinoid receptor expression and/or the action o...
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ژورنال
عنوان ژورنال: Clinical Chemical Laboratory Medicine
سال: 2007
ISSN: 1437-4331,1434-6621
DOI: 10.1515/cclm.2007.197